Suggested Use

Progesterone is very well absorbed through the skin when it is in a properly formulated bio-identical natural progesterone cream, such as Serenity, and unlike orally taken progesterone it is not intercepted by the liver. For this reason cream dosage is quite small. Serenity should be applied morning and bedtime to the fatty tissue areas of the body where it is stored for use as needed: buttocks, thighs, hips, breasts or upper arms and lower abdomen. It is important to massage the cream into a different area each time.

Women especially deficient in progesterone may take up to 3 months to achieve optimum levels.

A healthy woman will naturally manufacture 20-25mg of natural progesterone per day in the second half of her monthly cycle and the intention is to deliver this same amount of natural progesterone into the system with the cream. An eighth-teaspoon of Serenity contains 15mg of natural progesterone, so one application in the morning and one at bedtime will constitute a dosage of 30mg per day which, allowing for some wastage, will deliver the required net dose of 20-25mg per day; the same as should be produced naturally. If symptoms are severe you may use a quarter-teaspoon mornings and evenings, but all women are different and dosage should be assessed and modified by each individual through their own experience over a period of time - 'please note' below. Each jar contains over 90 eighth-teaspoon applications so a jar should last about 3 months for those having periods and 2 months for those on the 24 day regime.

Informed women have advised the following applications:

1. If you are still having periods: An eighth-teaspoon in the mornings and eighth-teaspoon at bed time massaged on a rotational basis; as described above, from day 14 of your cycle to day 28, then stop until day 14 of your next cycle. Count the first day of bleed as day one of the cycle. If your cycle is not the usual 28 day cycle, then use the cream as above from the mid point of your cycle to the end (ie if your cycle is every 24 days use Serenity from day 12 through to day 24, and then stop until day 12 of your next cycle).

2. If you are still having periods and are currently taking HRT: Serenity dosage as 1 above. You may wish to try cutting out HRT immediately at the outset of using Serenity or you may prefer to phase out the HRT over two months. To phase out HRT you must determine whether the HRT you are taking is an oestrogen and progestin combination and, if so, change to an oestrogen-only HRT treatment. (The combination of Natural Progesterone at the same time as a Synthetic Progestin is to be avoided). In the 1st month of using Serenity Natural Progesterone Cream and oestrogen-only HRT together:- Halve the dosage of HRT (to half of the normal HRT dosage). In the 2nd month halve the HRT dosage again (to a quarter of the normal HRT dosage). In month 3 cease HRT altogether.

   If you are having irregular periods and are approaching menopausal age: An eighth- teaspoon twice a day, mornings and bedtime for 24 days then discontinue for 6 days then repeat every month. If symptoms are severe you may increase this dosage to a quarter- teaspoon twice a day, but monitor progress and increase or decrease as required. If at any time you start a period then stop using the cream immediately, count that day as day 1, and start using the cream again on day 7 for 24 days. Serenity will not bring on a period if your body does not naturally require it.

3. If you are menopausal and are not having periods: An eighth-teaspoon twice a day, mornings and bedtime for 24 days, discontinue for 6 days then repeat every month. If symptoms are severe you may increase this dosage to a quarter-teaspoon twice a day, but monitor progress and increase or decrease as required. Using Serenity will not make periods start again.

4. If you have had a hysterectomy: Dosage of Serenity as in 3 above.

5. If you are menopausal or have had a hysterectomy and are currently taking HRT: Dosage of Serenity as in 3. You may wish to try cutting out HRT immediately at the outset of using Serenity, or you may prefer to phase out the HRT over a 2 month period. To do this you must first determine if the HRT you are taking is an oestrogen and progestin combination and if so, change to an oestrogen only treatment (the combination of Natural Progesterone at the same time as a Synthetic Progestin is to be avoided). In the 1st month of using Serenity Natural Progesterone Cream and oestrogen-only HRT together:- Halve the dosage of HRT (to half the normal HRT dosage). In the 2nd month halve the HRT dosage again (to a quarter of the normal HRT dosage) In month 3 cease HRT altogether.

6. If you have osteoporosis or wish to protect against osteoporosis: The use of Serenity in any of the above categories will stimulate osteoblast production which results in new bone tissue growth. Most osteoporosis sufferers will be menopausal and should use an eighth teaspoon mornings and an eighth teaspoon at bedtime for 24 days of the month and then discontinue for 6 days, repeating every month.

7. If you suffer from hot flushes or period related migraines: In addition to the above relevant dosage regime. For hot flushes, at the onset of a hot flush a dab of Serenity on the inside of each wrist may prove to be beneficial. At the onset of a migraine or severe headache a dab behind each ear and on the temples have proved to be of great help.

8. Infertility and loss of libido: The use of Serenity in any of the above categories will increase fertility and restore libido.

* Tip: Rub any residue on the face and neck, you will be amazed at skin tone improvement.

PLEASE NOTE: At the onset of using Natural Progesterone Cream a few women may experience an increase in "oestrogen dominance" symptoms. This is temporary and due to the Natural Progesterone waking up and making the oestrogen receptor sites more sensitive. If experienced, reduce Serenity to a tiny dot then build up gradually in the following weeks or until the symptoms subside, you may then resume normal application. There are no reported long term side effects to using transdermal bio-identical Natural Progesterone Cream. Oestrogen dominance can cause irregular cycles and retention of old blood. Because Natural Progesterone has a normalising effect on the menstrual cycle it can initially promote the shedding of this old blood. This shedding is desirable as old stored blood can increase the risk of endometrial cancer and endometriosis.